Generic Cialis serves as a budget-friendly yet equally potent alternative for ED management and usually available as tablets but there are alternative forms such as disintegrating strips, oral jelly, and sublingual troches. Tadalafil, while sharing similarities with Sildenafil, exhibits enhanced potency and efficacy, making it a more robust choice for addressing impotence.
Studies have also shown the effectiveness of Cialis in the treatment of lower urinary tract symptoms (LUTS) in patients with benign prostatic hyperplasia. It is a common condition in older men associated with a frequent need to urinate, urination obstructions, and even urinary tract infections.
How does Cialis affect erectile function?
Tadalafil inhibits a type 5 phosphodiesterase that leads to the breakdown of cyclic GMP. In turn, during sexual stimulation, cyclic GMP leads to the relaxation of the smooth muscles in the cavernous body of the penis, which provides increased blood flow and causes an erection. Thus, tadalafil supports the natural erection mechanism in the presence of sexual arousal.
Cialis can be taken regularly or on demand. Clinical data has shown similar efficacy with regular and on-demand tadalafil administration, but daily use has several advantages. Men who regularly use tadalafil 1 time per day noted less frequent headaches and nausea. It is assumed that these side effects are caused by a drop in tadalafil concentration in the blood, which is leveled by the regular dosing regimen. Patients taking tadalafil daily were successful in completing intercourse in 84% of cases. They also noted a higher frequency of morning erections, which had a positive effect on their self-confidence.
Orgasm and normal ejaculation are just as important as erection quality in determining male sexual satisfaction. Therapy with tadalafil from Canadian Med pharmacy at a dose of 10 or 20 mg promotes a subjective increase in ejaculatory and orgasmic function: in the treatment group, 66% of patients with severe ejaculatory disorders reported improvement. Accordingly, there was an improvement in 66% of patients with severe orgasm disorder.
Questions by Customers about Generic Cialis
When does Cialis reach peak concentration in the body?
You’ll have to wait for about a couple of hours. If the dosage is right for you, it will be active up to 36 hours in your body if you follow all intake recommendations.
Can I last longer with Cialis (Tadalafil)?
Yes, as well as Viagra, Cialis helps patients last longer while having sex and experience harder erections. Nevertheless, the potential side-effects and dangerous after-effects can last longer as well.
What’s wrong with the intake of grapefruit juice together with Cialis?
Grapefruit juice can either decrease or increase the levels of Tadalafil in the body and boost up its effectiveness. Of course, it might sound promising, but the unplanned increased levels of Tadalafil in your blood can lead to severe after-effects.
Will I get an erection with Cialis?
Cialis (Tadalafil) enhances the activity of specific chemicals in your body, thus making you experience a stronger erection. The penile area and the interior of your penis will get a sufficient amount of blood for stronger support and better sensitivity. You will only have to be sexually aroused. If you don’t find your partner physically appealing, a pill of Cialis will never help you.
Can I take a 20mg dose more than a couple of days in a row?
You can take Generic Cialis daily, but you shouldn’t take a 10mg or a 20 mg dose daily — these dosage options should be taken once before sexual activity. Continuous use of maximum Cialis options is dangerous for blood pressure and heart muscle functionality.
Is Cialis better than Viagra?
Both Cialis and Viagra are evenly effective for daily use. Viagra is more expensive, but it’s a time-trusted medicine. Cialis is released in a wider range of dosage options and works up to 36 hours. Viagra cannot be taken as the weekend pill, while Cialis can.
Can I split the pill if I need a lower dosage?
Cutting and splitting pills into halves can affect the way your body reacts to the medication. It does not depend on the kind of tablet you take. You’d better take time and find the appropriate dosage so that you won’t have to split the pill.
What should I do if Cialis does not prove to be effective?
Most ED medications get active within 3 hours. If you follow all doctor’s recommendations but still don’t feel the effect, you might have underlying problems. A few tries or a higher dose can manage the problem. If the med does not work, you should consider another medical check-up or a blood analysis to find out more about the malfunctions of your body.
What will too much Tadalafil do to me?
One of the most severe overdose effects is a prolonged erection that might last for 4 hours or even more. It’s a very painful process, and you should not tolerate the pain if you feel it. Let the doctor intervene very quickly.
Intake and Dosing Tips
- Schedule the intake of Cialis and try to take a pill every day at the same time;
- 10mg pills make up a starting dose, but you should consult the physician first — 5mg and 2.5mg doses are more preferable;
- If the med is not working after the first intake, don’t get worried — let Cialis (Tadalafil) get to a sufficient concentration in your body;
- It does not matter how you take Cialis — with or without food is acceptable;
- Make sure you don’t go too far with alcohol;
- Avoid eating grapefruit and drinking grapefruit juice — it often cancels the effect of the medication.
Efficacy and safety of Cialis in clinical trials
Currently, more than 90 clinical studies have been conducted (including long-term studies lasting up to 2 years), during which the efficacy and safety of tadalafil have been unambiguously proven. To assess its clinical efficacy and safety, an integrative analysis of five randomized, double-blind, placebo-controlled studies was carried out in 1999–2001 in 74 medical centers and covered 1,112 men aged 22 to 82 years who suffered from moderate or severe ED (61% organic, 9% psychogenic, and 31% mixed in nature). Patients received tadalafil at a daily dose of 2.5 mg, 5 mg, 10 mg, 20 mg, or placebo with no restrictions on food and alcohol consumption. At the end of treatment, 81% of men reported improved erections. The efficacy of the drug was the same in young patients and persons over 65 years of age. It also did not depend on the origin of ED.
Tadalafil has demonstrated its effectiveness in men suffering from multiple sclerosis, which indicates the possibility of its use even in severe somatic pathology. Data obtained in recent years confirm the efficacy and good tolerability of tadalafil in clinical practice. In particular, the drug had a significantly positive effect on men taking antidepressants and suffering from this sexual dysfunction.
Adverse Effects and Warnings
Tadalafil acts more selectively in relation to PDE5, which ensures fewer side effects, including from the side of vision. However, tadalafil is more likely to cause myalgia and back pain compared to sildenafil (Viagra) and vardenafil (Levitra).
The most common side effects of tadalafil, when taken daily, are headache (1–14%), dyspepsia (1–11%), facial flushing (7–8%), nasal congestion (6–7%), back pain (2–11%), myalgia (1–5%), abdominal pain (3–9%), and dizziness (1–4%). In the course of studies conducted on the daily intake of tadalafil, no serious side effects were recorded. As a rule, over time, the frequency of side effects decreases. After eight weeks, the frequency of side effects is on average reduced by half.
Cialis is contraindicated to men who take nitrates (nitroglycerin, isosorbide dinitrate, and isosorbide-5-mononitrate, used for prophylaxis and management of acute coronary syndromes, myocardial infarction, and heart attacks).
People with renal and hepatic insufficiency should take Cialis with caution.
Treatment of erectile dysfunction with PDE5 inhibitors should not be prescribed to men with heart conditions in which sexual activity is not recommended. Tadalafil should be used with caution in men with a predisposition to priapism or anatomical deformity of the penis. In the event of an erection lasting 4 hours or more, you should immediately consult a doctor.
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